A SHORT REVIEW ON RECENT DEVELOPMENTS IN TMD FACTORIZATION AND IMPLEMENTATION


Introduction of a More Glutaredoxin-like Active Site to PDI Results in Competition between Protein Substrate and Glutathione Binding

Proteins in the thioredoxin superfamily share a similar fold, contain a -CXXC- active site, and catalyze oxidoreductase reactions by dithiol-disulfide exchange mechanisms.Protein disulfide isomerase (PDI) has two -CGHC- active sites.For in vitro studies, oxidation/reduction of PDI during the catalytic cycle is accomplished with glutathione.Glutathi

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Total arterial myocardial revascularization in octogenarians

According to the current ESC/EACTS Selenium Myocardial Revascularization Guidelines, the left internal mammary artery (LIMA) should always be implanted to graft the left anterior descending (LAD) artery, but an additional arterial graft should be considered in appropriate patients undergoing coronary artery bypass grafting (CABG) [1].In spite of in

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